Abstract #0150

MRI-guided real-time 4D Radiation Dosimetry at an MRI-Linac using Polymer Gel Dosimeters

Yves De Deene¹, Morgan Wheatley², Gary Liney³, David Waddington⁴, Urszula Jelen³, and Bin Dong³

¹Engineering, Macquarie University, North Ryde - Sydney, Australia, ²Macquarie University, North Ryde - Sydney, Australia, ³Ingham Institute, Liverpool, Australia, ⁴The University of Sydney, Sydney, Australia

4D radiation dosimetry using a highly radiation-sensitive polymer gel dosimeter with real-time quantitative MRI readout is presented as a technique to acquire the accumulated radiation dose distribution during image guided radiotherapy (IGRT) in an MRI-Linac. Optimized T₂ weighted TSE scans are converted to quantitative R₂ maps and subsequently to radiation dose maps. A further increase in temporal resolution using a keyhole imaging approach is proposed. The potential use of real-time 4D radiation dosimetry for safeguarding image guided radiotherapy (IGRT) of moving and deforming targets in an MRI-Linac will be discussed.

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