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Abstract #0158

Multimodal quantitative arterial-venous segmentation of the human brain at 7T: structure, susceptibility and flow

Michaƫl Bernier1,2, Berkin Bilgic1,2, Saskia Bollmann1,2, Nina E. Fultz1,3, and Jonathan R. Polimeni1,2,4
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Radiology, Harvard Medical School, Boston, MA, United States, 3Engineering, Boston University, Boston, MA, United States, 45Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Vascular imaging acquisition techniques to extract veins and arteries are not impervious to flaws: venography by susceptibility weighted imaging is prone to blooming effects and false-negatives, and angiography from time-of-flight imaging is affected by veins detection and false-negatives. They also fail to provide quantitative measures of vascular physiology such as flow and susceptibility important for understanding the origin of vascular-based biases. Thus, we aimed to employ multi-orientation quantitative susceptibility mapping, multi-echo time-of-flight and quantitative phase-contrast to more accurately detect and quantify the susceptibility and flow along the vascular tree, paving the way for a joint anatomical/physiological vascular atlas at 7T.

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