Cervical cancer recurs post-trachelectomy often because of close surgical margins or lymph-node micrometastases. We show that 5 texture features distinguish good- from poor-prognosis tumors (low/high volume, without/with parametrial invasion, without/with lymph node metastases). For tumors suitable for trachelectomy (<4.19cm3), linear regression of feature value with volume (using 3 features with high discrimination of groups and 1 standard deviation from median from good prognosis group as threshold) indicated that radiomic features tended towards values representing poor prognosis at 1.8±0.2cm3 (T2-W images) and 1.8±0.06cm3 (ADC maps). Above 1.8cm3 textural features of cervical cancer shift towards a phenotype likely to spread and metastasize.
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