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Abstract #0289

Utility of computed diffusion-weighted imaging for evaluating primary prostate cancer in whole-body MRI

Yuki Arita1,2, Yuma Waseda3, Soichiro Yoshida2,3, Taro Takahara2,4, Chikako Ishii2, Thomas C Kwee5, Ryota Ishii6, Shigeo Okuda1, Yasuhisa Fujii3, and Masahiro Jinzaki1
1Department of Radiology, Keio University School of Medicine, Tokyo, Japan, 2Department of Radiology, Advanced Imaging Center Yaesu Clinic, Tokyo, Japan, 3Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan, 4Department of Biomedical engineering, Tokai University School of Engineering, Kanagawa, Japan, 5Department of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands, 6Department of Biostatistics Unit, Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan

The purpose of this study is to determine the value of applying computed DWI to a whole-body MRI/DWI protocol to acquire computed high b-value (2000 s/mm2) diffusion-weighted images for local prostate cancer evaluation. Based on the results, computed diffusion-weighted images obtained from whole-body MRI provide a similar diagnostic performance compared to pelvic bi-parametric MRI for the detection of primary prostate cancer. Computed DWI is a straightforward postprocessing technique without the need for additional image acquisition time. It can be recommended for use in routine clinical practice in whole-body MRI protocols for concurrent evaluation of primary and metastatic prostate cancer.

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