Abstract #0289

Utility of computed diffusion-weighted imaging for evaluating primary prostate cancer in whole-body MRI

Yuki Arita^1,2, Yuma Waseda³, Soichiro Yoshida^2,3, Taro Takahara^2,4, Chikako Ishii², Thomas C Kwee⁵, Ryota Ishii⁶, Shigeo Okuda¹, Yasuhisa Fujii³, and Masahiro Jinzaki¹

¹Department of Radiology, Keio University School of Medicine, Tokyo, Japan, ²Department of Radiology, Advanced Imaging Center Yaesu Clinic, Tokyo, Japan, ³Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, Japan, ⁴Department of Biomedical engineering, Tokai University School of Engineering, Kanagawa, Japan, ⁵Department of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands, ⁶Department of Biostatistics Unit, Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan

The purpose of this study is to determine the value of applying computed DWI to a whole-body MRI/DWI protocol to acquire computed high b-value (2000 s/mm²) diffusion-weighted images for local prostate cancer evaluation. Based on the results, computed diffusion-weighted images obtained from whole-body MRI provide a similar diagnostic performance compared to pelvic bi-parametric MRI for the detection of primary prostate cancer. Computed DWI is a straightforward postprocessing technique without the need for additional image acquisition time. It can be recommended for use in routine clinical practice in whole-body MRI protocols for concurrent evaluation of primary and metastatic prostate cancer.

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