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Abstract #0327

Modifying LI-RADS on gadoxetate disodium-enhanced MRI in a prospective cohort: toward improving simplicity and sensitivity

Hanyu Jiang1,2, Bin Song1, and Mustafa Shadi Rifaat Bashir2
1Department of Radiology, West China Hospital, Sichuan University, Chengdu, China, 2Department of Radiology, Duke University Medical Center, Durham, NC, United States

We aimed to develop a modified Liver Imaging Reporting and Data System (mLI-RADS) with comparisons against original LI-RADS version 2018 (v2018) for diagnosing hepatocellular carcinoma (HCC) on gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI). 1002 hepatic observations in 272 consecutive at-risk patients were prospectively included. Ancillary features were assessed based on inter-rater agreement, prevalence, diagnostic accuracy, and added value to the major features. Compared with the original LI-RADS v2018, mLI-RADS demonstrated superior simplicity, sensitivity and accuracy without substantial loss of specificity; hence should be the preferred diagnostic criteria for HCC in high-risk patients on EOB-MRI.

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