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Abstract #0618

Multi-frequency wave-encoding (mf-wave) on gradients and multi-coil shim-array hardware for highly accelerated acquisition

Jinmin Xu1,2, Jason Stockmann2, Berkin Bilgic2, Thomas Witzel2,3, Jaejin Cho2, Congyu Liao2, Zijng Zhang1,2, Huafeng Liu1, and Kawin Setsompop2,3,4
1State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China, 2Department of Radiology, A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Harvard Medical School, Boston, MA, United States, 4Massachusetts Institute of Technology, Harvard-MIT Health Sciences and Technology, Cambridge, MA, United States

Wave-CAIPI is a parallel imaging technique that can provide high accelerations with negligible g-factor and artifact penalties. However, gradient amplitude & slew rate limits impose a limitation on the amount of wave-encoding and hence the acceleration capability of this technique. In this study, we propose a multi-frequency wave-encoding method (mf-wave) that uses both the gradients and a combined RF and B0 shim array (32-channel) to perform wave-encoding simultaneously and synergistically at different wave frequencies during the acquisition. We demonstrate that mf-wave can enable ~20-fold acceleration with an acceptable g-factor noise penalty at 3T in vivo.

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