SPatiotemporal ENcoding (SPEN) is a 2D single-shot MRI method with higher immunity to artifacts than EPI-based counterparts. The present study extends SPEN scans to 3D volumetric measurements, to achieve imaging over a 3rd dimension at higher resolution in minimal acquisition times. simultaneous multi-slab (SMS) and multi-echo (ME) kz-encoding procedures are here combined to cope with the SAR complications that would ensue from simply repeating 2D acquisitions over multiple slices. A framework to appropriately reconstruct and process 3D SMS-ME SPEN data to ensure the image quality by taking motion artifacts derived from different dimensions into account is also proposed, and demonstrated.
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