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Abstract #0836

3D Amide proton transfer weighted imaging in predicting Ki-67 proliferation state of rectal adenocarcinoma

Ling Li1, Yingjie Mei2, Zhaoxian Yan3, Jieping Feng3, Bo Liu3, and Xian Liu3
1Guangzhou University of Chinese Medicine; The second Affiliated hospital of Guangzhou University of Chinese Medicine;, Guangzhou, China, 2Clinical Science,Philips Healthcare;, Shanghai, China, 3Radiology, The second Affiliated hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

The Accurate preoperative staging and grading are significant on the treatment of protocol selection rectal adenocarcinoma. As a new molecular MR imaging technique, APT imaging could provide information that correlates with tumor cell proliferation. In this study, the capability of APT in differentiating WHO grades and pathologic stages of rectal adenocarcinoma was investigated and compared with DWI. The results show that APT value have a significantly positive correlation with the stage and grade of the rectal adenocarcinoma, and the prognosis factor Ki67.

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