Abstract #0839

Value of quantitative DCE and DW-MRI in predicting extramural venous invasion in locally advanced gastric cancer and the prognostic significance

Yongjian Zhu¹, Ying Li¹, Jun Jiang¹, Yutao Zhou¹, Liming Jiang¹, Liyan Xue², and Lizhi Xie³

¹Department of Imaging Diagnosis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ²Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ³GE healthcare, China, Beijing, China

Extramural vascular invasion (EMVI) has been found as an independent risk factor for recurrence and distant metastasis in patients with gastric cancer. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) has been applied in diagnosis of different cancers. In this study, we research into the value of DCE-MRI parameters and ADC in predicting EMVI and the prognostic significant. It was found that K^trans, V_e and ADC are independent predictors of pathological EMVI in LAGC, and MRI-predicted EMVI (mrEMVI) confirmed to be a poor prognosis predictor in terms of 2-year recurrence-free survival (RFS).

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