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Abstract #0839

Value of quantitative DCE and DW-MRI in predicting extramural venous invasion in locally advanced gastric cancer and the prognostic significance

Yongjian Zhu1, Ying Li1, Jun Jiang1, Yutao Zhou1, Liming Jiang1, Liyan Xue2, and Lizhi Xie3
1Department of Imaging Diagnosis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 3GE healthcare, China, Beijing, China

Extramural vascular invasion (EMVI) has been found as an independent risk factor for recurrence and distant metastasis in patients with gastric cancer. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) has been applied in diagnosis of different cancers. In this study, we research into the value of DCE-MRI parameters and ADC in predicting EMVI and the prognostic significant. It was found that Ktrans, Ve and ADC are independent predictors of pathological EMVI in LAGC, and MRI-predicted EMVI (mrEMVI) confirmed to be a poor prognosis predictor in terms of 2-year recurrence-free survival (RFS).

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