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Abstract #0870

Liver Dixon MR Fingerprinting: T1, T2, T2* and fat fraction tissue characterization

Olivier Jaubert1, Cristobal Arrieta2,3, Gastao Cruz1, Aurelien Bustin1, Torben Schneider4, Georgios Georgiopoulos1, Pier-Giorgio Masci1, Carlos Sing-Long3,5,6, Rene Michael Botnar1, and Claudia Prieto1
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile, 3Millennium Nucleus for Cardiovascular Magnetic Resonance, Santiago, Chile, 4Philips Healthcare, London, United Kingdom, 5Instituto de Ingeniería Matemática y Computacional, Pontificia Universidad Católica de Chile, Santiago, Chile, 6Millennium Nucleus Center for the Discovery of Structures in Complex Data, Chile, Santiago, Chile

Quantitative T1, T2, T2* and fat fraction (FF) maps are promising imaging biomarkers for the assessment of liver disease. Magnetic Resonance Fingerprinting has been recently proposed for fast T1, T2 and M0 mapping of the liver, however in the presence of high iron or fat concentrations corrections using separately acquired T2* and FF maps are needed. Here we propose a novel approach which enables simultaneous liver T1, T2, T2* and FF maps from a single ~15s breath-hold scan. The proposed approach was evaluated on phantoms, 8 healthy subjects and 2 patients in comparison to conventional mapping techniques.

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