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Abstract #0961

Overcoming geometric distortions in human prostate diffusion weighted imaging by spatio-temporal encoded (SPEN) MRI

Martins Otikovs1, Lingceng Ma1, and Lucio Frydman1
1Weizmann Institute of Science, Rehovot, Israel

Spatiotemporal encoding (SPEN) is an alternative ultrafast imaging technique which allows one to manipulate the bandwidth along the phase-encoding (PE) direction as well as to achieve T2* refocusing throughout the FID acquisition, thereby overcoming distortions observed along EPI’s PE dimension. The study compares multislice 2D SPEN and a 3D SPEN sequence variants against EPI derivatives, evaluating their ability to deliver prostate diffusion-weighted imaging (DWI) data and apparent diffusion coefficient (ADC) maps on healthy human volunteers. Essentially distortion-free diffusion weighted images and ADC maps of prostate with good SNR were achieved by the 2D SPEN variant.

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