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Abstract #0963

Acquisition of a reference Connectom diffusion MRI dataset: In vivo whole-brain diffusion MRI at 760 µm isotropic averaged over 18 hours

Fuyixue Wang1,2, Zijing Dong1,3, Qiyuan Tian1, Congyu Liao1, Qiuyun Fan1, W. Scott Hoge4, Chanon Ngamsombat1, Boris Keil5, Jonathan R. Polimeni1,2, Lawrence L. Wald1,2, Susie Y. Huang1,2, and Kawin Setsompop1,2
1A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 33Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 4Department of Radiology, Brigham and Women's Hospital, Boston, MA, United States, 5Department of Life Science Engineering, Institute of Medical Physics and Radiation Protection, Giessen, Germany

We present a whole brain in vivo diffusion MRI dataset acquired at 760um isotropic resolution and sampled at 1260 q-space points across 9 two-hour sessions. The creation of this benchmark in vivo diffusion MRI dataset is possible through use of the Connectom scanner, custom-built 64-channel phased-array coil, gSlider acquisition, dual-polarity GRAPPA reconstruction, reverse phase encoding for distortion mitigation, and personalized motion-robust stabilizer. The data will enhance our understanding of gray and white matter structure with fine detail revealed at sub-mm resolution and serve as a reference dataset for new modeling and processing algorithms.

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