Abstract #0980

Phase-matched Self-calibrated K-space Phase Correction Method for Multi-shot Diffusion Imaging

Zhe Zhang¹, Xiaodong Ma², Lanxin Ji¹, Jing Jing¹, Wanlin Zhu¹, Zhangxuan Hu³, Yishi Wang⁴, Hua Guo³, and Yongjun Wang^1,5

¹China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijng, China, ²Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ³Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ⁴Philips Healthcare, Beijing, China, ⁵Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Multi-shot acquisition enables high-resolution diffusion imaging, but the artifacts caused by shot-to-shot phase variation must be corrected. Self-calibrated multi-shot DWI methods utilize parallel imaging reconstruction to solve the phase of each shot. Previously reported self-calibrated GRAPPA with a compact kernel (SC-ckGRAPPA) method is compromised by the high reduction factor when recovering the navigator information. In this work, PM-SC-ckGRAPPA was introduced with the phase-matched reconstruction, and evaluated via in-vivo experiment. Results show that PM-SC-ckGRAPPA provides improved reconstruction compared with conventional approaches, and PM-SC-ckGRAPPA can be a potential tool for high-resolution diffusion imaging.

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