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Abstract #1019

Dynamic Water, Fat, R2* and B0 Field Inhomogeneity Quantification Using Multi-Echo Multi-Spoke Radial FLASH

Zhengguo Tan1,2, Peter Dechent3, Xiaoqing Wang1,2, Nick Scholand1,2, Dirk Voit4, Jens Frahm2,4, and Martin Uecker1,2
1Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany, 2German Center for Cardiovascular Research (DZHK), Göttingen, Germany, 3Cognitive Neurology, University Medical Center Göttingen, Göttingen, Germany, 4Biomedizinische NMR, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

To achieve dynamic and simultaneous access to R2* relaxation rates, B0 field inhomogeneities and water/fat separation, we developed a model-based reconstruction technique on BART for continuous acquisitions based on undersampled multi-echo multi-spoke radial FLASH. Beside spatial smoothness constraints on coil sensitivity and B0 field maps, L1 wavelet regularization is applied to the water, fat and R2* maps. Preliminary results of brain fMRI data demonstrate significant T2* change from 37 to 67 ms in the occipital visual cortex. In addition, R2* mapping of free-breathing liver with only 15 RF shots per frame (194 ms temporal resolution) reveals increased R2* during inspiration.

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