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Abstract #1042

Numerical simulation of 4D Flow MRI

Thomas Puiseux1,2, Anou Sewonu1,3, Ramiro Moreno1,3,4, Simon Mendez2, and Franck Nicoud2
1SPIN UP, Toulouse, France, 2IMAG, Univ. Montpellier, CNRS, Montpellier, France, 3I2MC, INSERM U1048, Toulouse, France, 4ALARA Expertise, Strasbourg, France

The present study proposes a novel approach to efficiently simulate 4D Flow MRI acquisitions in realistic complex flow conditions. Navier-Stokes and Bloch equations are simultaneously solved with Eulerian-Lagrangian coupling. A semi-analytic solution for the Bloch equation as well as a periodic particle re-injection strategy are implemented to reduce the computational cost. The Bloch solver and the velocity reconstruction pipeline were first validated in a steady flow configuration. The coupled 4D Flow MRI simulation procedure was validated in a complex pulsatile flow phantom cardiovascular-typical experiment. Besides, we compared simulated MR velocity data with experimental 4D Flow MRI measurements.

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