Resting-state fMRI studies are conducted with eyes-closed (EC) or eyes-open (EO) conditions. Given differences in spontaneous activity between EO and EC conditions, metabolic foundations of fMRI-derived networks, specifically activated (e.g., sensory network) and deactivated (e.g., default mode network, DMN) nodes, are poorly understood. We assessed aerobic glycolysis and excitatory-inhibitory balance in healthy volunteers’ visual cortex (VC, a non-DMN node) and posterior cingulate cortex (PCC, a DMN node) using J-edited fMRS and calibrated fMRI. Functional changes between EO and EC conditions are regionally non-specific to aerobic glycolysis and flow-metabolism coupling, but neurovascular coupling in VC depends on EO and EC conditions.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords