In this study, a fast 3D MR fingerprinting sequence with water and fat separation (3D MRF T1-FF) was developed for simultaneous measurement of FF and water T1 in the skeletal muscles of patients with fat infiltrations. The precision and accuracy of the sequence was evaluated on a multi-vial phantom and in vivo proofs of concept were obtained in the legs of a healthy volunteer before and after plantar dorsi-flexions and at rest in a patient suffering from inclusion body myositis.
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