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Abstract #1187

Multi-parametric diffusion tensor imaging  for early detection of dysthyroid optic neuropathy during thyroid-associated ophthalmopathy

Ping Liu1, Gui-hua Jiang1, and Jing Zhang2
1Radiology, Guangdong Second Provincial General Hospital, Guangzhou, China, 2Radiology, The Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China

Dysthyroid optic neuropathy (DON) is the most serious complication of Thyroid-Associated Ophthalmopathy(TAO). Untimely and ineffective treatment of could lead to permanent blindness. Early detection is the principle factor for timely intervention. Diffusion tensor imaging(DTI) is a noninvasive tool to reveal microstructural or non-overt damage and quantify pathological processes of nerve fiber bundle. We applied the multi-parametric of optic nerve to identify the DON from TAO. The result reveals that DTI can be considered a useful and noninvasive tool to differentiate DON from TAO with higher accuracy.

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