Abstract #1213

Reproducibility, Repeatability and Preliminary Clinical Results of Dixon Cardiac MRF: T1, T2, ECV and fat fraction tissue characterization

Olivier Jaubert¹, Gastao Cruz¹, Aurelien Bustin¹, Torben Schneider², Georgios Georgiopoulos¹, Mariya Doneva³, Pier-Giorgio Masci¹, Rene Michael Botnar¹, and Claudia Prieto¹

¹Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²Philips Healthcare, London, United Kingdom, ³Philips Research Hamburg, Hamburg, Germany

Dixon cardiac Magnetic Resonance Fingerprinting (DcMRF) has been recently proposed to enable simultaneous water T₁, water T₂ and fat fraction (FF) quantification in a single breath-hold scan. Here we investigate the reproducibility, repeatability and clinical feasibility of DcMRF in comparison to reference MOLLI, T2GRASE and 6 echo proton density FF measurements. Reproducibility and repeatability were investigated in healthy subjects, whereas native T₁, T₂ and FF, and post contrast T₁ and synthetic ECV measurements were performed in patients with suspected cardiovascular disease.

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