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Abstract #1213

Reproducibility, Repeatability and Preliminary Clinical ResultsĀ of Dixon Cardiac MRF: T1, T2, ECV and fat fraction tissue characterization

Olivier Jaubert1, Gastao Cruz1, Aurelien Bustin1, Torben Schneider2, Georgios Georgiopoulos1, Mariya Doneva3, Pier-Giorgio Masci1, Rene Michael Botnar1, and Claudia Prieto1
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Philips Healthcare, London, United Kingdom, 3Philips Research Hamburg, Hamburg, Germany

Dixon cardiac Magnetic Resonance Fingerprinting (DcMRF) has been recently proposed to enable simultaneous water T1, water T2 and fat fraction (FF) quantification in a single breath-hold scan. Here we investigate the reproducibility, repeatability and clinical feasibility of DcMRF in comparison to reference MOLLI, T2GRASE and 6 echo proton density FF measurements. Reproducibility and repeatability were investigated in healthy subjects, whereas native T1, T2 and FF, and post contrast T1 and synthetic ECV measurements were performed in patients with suspected cardiovascular disease.

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