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Abstract #1257

In vivo Two-photon Magnetic Resonance Imaging of Human Hand at 1T

Jianshu Chi1, Victor Han1, and Chunlei Liu1,2
1Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, 2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States

We demonstrate the first in vivo imaging experiment with a multiphoton excitation technique at 1T. To produce multiphoton excitation, we built a secondary RF coil that produces an RF field, parallel to the $$$B_{0}$$$ field. Designed for kHz frequencies, this coil consists with two layers of traces in a spiral configuration on a printed circuit board (PCB). Adding this low-frequency coil to an Aspect 1T Wrist Scanner, we acquired gradient echo images with two-photon excitation of a human hand in vivo.

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