Evaluating white matter hyperintensities (WMHs) in neuropsychiatric systemic lupus erythematosus (NPSLE) is a challenging task. Multimodal MRI images in combination with unsupervised machine characterization can provide a powerful tool to investigate the spatial WHM distribution of relevant phenotypes. Automatically segmented WMH maps were spatially allocated to a white matter tract atlas. Cluster analysis was applied on this tract-wise lesion-load map to obtain subtypes with a distinct WMH damage profile. This approach on microstructural changes could help to identify specific progression pattern which may improve the accuracy of NPSLE classification.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords