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Abstract #1313

High resolution spiral simultaneous multi‐slice first‐pass perfusion imaging with whole-heart coverage at 1.5 T and 3 T

Junyu Wang1, Yang Yang2,3, Ruixi Zhou1, Changyu Sun1, Mathews Jacob4, Daniel S. Weller5, Frederick H. Epstein1,6, and Michael Salerno1,3,6
1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2Biomedical Engineering and Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Medicine, University of Virginia, Charlottesville, VA, United States, 4Electrical and Computer Engineering, University of Iowa, Iowa City, IA, United States, 5Electrical and Computer Engineering, University of Virginia, Charlottesville, VA, United States, 6Radiology, University of Virginia, Charlottesville, VA, United States

First-pass contrast-enhanced myocardial perfusion imaging is a useful noninvasive tool to evaluate patients with known or suspected coronary artery disease, but current techniques are still limited in spatial-temporal resolution and ventricular coverage. We designed a spiral pulse sequence with simultaneous multi-slice (SMS) acquisition and utilized the SMS-L1-SPIRiT reconstruction technique to achieve ultra-high resolution (1.5 mm at 1.5 T and 1.25 mm at 3 T) perfusion imaging with whole-heart coverage. The proposed spiral SMS perfusion acquisition strategy was tested on heathy volunteers and clinical patients. High image quality was demonstrated with an SMS factor of 3 at both 1.5T and 3T.

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