First-pass contrast-enhanced myocardial perfusion imaging is a useful noninvasive tool to evaluate patients with known or suspected coronary artery disease, but current techniques are still limited in spatial-temporal resolution and ventricular coverage. We designed a spiral pulse sequence with simultaneous multi-slice (SMS) acquisition and utilized the SMS-L1-SPIRiT reconstruction technique to achieve ultra-high resolution (1.5 mm at 1.5 T and 1.25 mm at 3 T) perfusion imaging with whole-heart coverage. The proposed spiral SMS perfusion acquisition strategy was tested on heathy volunteers and clinical patients. High image quality was demonstrated with an SMS factor of 3 at both 1.5T and 3T.
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