Abstract #1333

Longitudinal study of 4D flow MRI derived aortic hemodynamics in bicuspid aortic valve patients with repaired coarctation.

Gilles Soulat¹, Michael Scott¹, Ashitha Pathrose¹, Kelly Jarvis¹, Haben Berhane², Bradley Allen¹, Ryan Avery¹, Cynthia Rigsby², and Michael Markl³

¹Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ²Department of Medical Imaging, Ann & Robert H. Lurie Children’s Hospital of Chicago,, Chicago, IL, United States, ³Department of Radiology, Feinberg School of Medicine, and Department of Biomedical Engineering, McCormick School of Engineering; Northwestern University, Chicago, IL, United States

Bicuspid aortic valve (BAV) patients with history of aortic coarctation are considered higher risk for aortic complications. We evaluated 4D flow aortic metrics in 15 BAV adults with coarctation repair (mean age 35y) retrospectively reviewed at baseline and follow-up (3.98y [2.10 to 4.96y ]). Areas of higher wall shear stress were mainly located in the arch, and 4D flow metrics remained stable at follow-up. Aortic growth was slow, with a significant increase in the anterior arch (0.25mm/y) and diaphragmatic aorta (0.27mm/y). At baseline, peak velocity at the coarctation repair site was inversely correlated to mid arch and diaphragmatic aortic growth.

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