Abstract #1342

Simultaneous whole brain resting state fMRI and full-spectrum electrophysiology in rodents

Wenyu Tu¹, Yuncong Ma², Thomas Neuberger², and Nanyin Zhang²

¹The Huck Institutes of the Life Sciences, Penn State University, University Park, PA, United States, ²Biomedical Engineering, Penn State University, University Park, PA, United States

To elucidate the neural basis of resting state functional network, it is important to continuously record neural activity during rsfMRI. In this study, we developed a platform including animal setup and a signal denoising pipeline to achieve continuous measurement of local field potential (LFP) and neuronal spikes with simultaneous whole-brain rsfMRI in rats.

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