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Abstract #1400

"Comparative analysis of 3D DIR and 3D FLAIR in  cases  of  acute  optic  neuritis"

Vivek Shriram Murumkar1, Jitender Saini1, Nethravati Manjunath2, Dhritiman Chakraborty3, and Rakesh Gupta4
1Neuroimaging and interventional radiology, national institute of mental health and neuroscineces (NIMHANS) bangalore, india, Bangalore, India, Bangalore, India, 2Neurology, national institute of mental health and neuroscineces (NIMHANS) bangalore, india, Bangalore, India, Bangalore, India, 3Neuroanaesthesia, national institute of mental health and neuroscineces (NIMHANS) bangalore, india, Bangalore, India, Bangalore, India, 4radiology, Fortis Hospital, Gurugram, India

Optic neuritis is presenting feature in 15-20% cases of MS and 50% cases of MS have optic neuritis during course of illness. Signals from CSF and intraorbital fat are main hurdles in optic nerve imaging, 3D FLAIR and 3D DIR are used to study optic nerve pathologies as they suppress fat and CSF signals. DIR nulls signal from NAWM providing inherent contrast. 3D DIR and 3D FLAIR was done in 31 case of acute optic neuritis and 30 controls. We found higher contrast rates, sensitivity and negative predictive value for the 3D DIR than 3D FLAIR in acute optic neuritis

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