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Abstract #1599

Association between type 2 diabetes mellitus and characteristics of intracranial atherosclerotic plaque: a high-resolution MRI study

Sheng Jiao1, Juan Huang2, Yan Song2, Yuhui Chen3, Chengwen Liu4, Jinxia Zhu4, Jintao Zhang2, and Min Chen2
1Radiology, Beijing hospital, Beijing, China, 2Radiology, Beijing Hospital, Beijing, China, 3Neurology, Beijing Hospital, Beijing, China, 4MR Collaboration, Siemens Healthcare Ltd., Beijing, China

In this study we used high-resolution MRI to image intracranial atherosclerotic plaque more precisely, and then characteristics of plaque were obtained to compare with the blood glycemic (BG) level in Type 2 Diabetes mellitus (T2DM). Results demonstrated that patients with poor BG control had heavier intracranial plaque burden and more vulnerability than the patients without DM. While compared with non-DM, patients with good BG control showed no significant different in plaque burden. It suggested that BG level is an independent risk factor for the vulnerability of the intracranial atherosclerotic plaque.

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