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Abstract #1606

Quantitation of penumbra volumes in acute ischemic stroke using susceptibility- weighted imaging and mapping

Xiudi Lu1, Linglei Meng2, Yongmin Zhou3, Shaoshi Wang2, Miller Fawaz4, Meiyun Wang5, E. Mark Haacke4, Chao Chai6, Meizhu Zheng7, Jinxia Zhu8, Shuang Xia6, and Yu Luo3
1The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China, 2Shanghai Fourth People’s Hospital, Shanghai, China, 3Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine, Shanghai, China, 4Wayne State University, Detroit, MI, United States, 5Zhengzhou University People’s Hospital, Zhengzhou, China, 6Tianjin First Central Hospital, Tianjin, China, 7Third Central Hospital of Tianjin, Tianjin, China, 8Siemens Healthcare Ltd, Beijing, China

This study aimed to measure ischemic penumbra volumes using susceptibility-weighted imaging and mapping (SWIM). We compared the diagnostic accuracy between SWIvolume-diffusion-weighted imaging (DWI) and SWIASPECTS-DWI mismatches and analyzed the relationships among the SWIvolume-DWI, SWIASPECTS-DWI, and PWI-DWI mismatches and the different parameters and NIHSS. We found that quantitative SWIvolume-DWI mismatch volumes were more accurate than those of the SWIASPECTS-DWI mismatch in being able to evaluate ischemic penumbra. The asymmetrical prominent cortical vein volumes using SWIM showed hypoperfused regions and Tmax >6s volumes, based on perfusion-weighted imaging (PWI). The quantitative SWIvolume-DWI mismatch was highly consistent with the PWI-DWI mismatch.

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