This study aimed to investigate atherosclerotic plaque characteristics in middle cerebral artery (MCA) atherosclerotic patients with border-zone (BZ) infarction using magnetic resonance vessel wall imaging (MR-VWI). In 84 retrospectively enrolled ischemic stroke patients caused by MCA atherosclerosis, the characteristics of culprit plaques were quantitatively compared between BZ only infarction and combined border-zone and pial (BZ+PI) infarction groups. BZ+PI infarction was associated with a higher degree of stenosis and higher plaque-wall contrast ratio and enhancement ratio, compared with BZ only infarction, suggesting that embolic pathogenesis may also account for BZ+PI infarction in addition to hemodynamic compromise.
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