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Abstract #1614

Plaque characteristics and implication on mechanism in border-zone infarction caused by middle cerebral artery atherosclerosis

Yu Guo1,2, Jiayu Xiao2, Zhongying Gong3, Wen Shen1, Shuang Xia1, and Zhaoyang Fan2
1Radiology, Tianjin First Central Hospital, tianjin, China, 2BIRI, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 3Neurology, Tianjin First Central Hospital, tianjin, China

This study aimed to investigate atherosclerotic plaque characteristics in middle cerebral artery (MCA) atherosclerotic patients with border-zone (BZ) infarction using magnetic resonance vessel wall imaging (MR-VWI). In 84 retrospectively enrolled ischemic stroke patients caused by MCA atherosclerosis, the characteristics of culprit plaques were quantitatively compared between BZ only infarction and combined border-zone and pial (BZ+PI) infarction groups. BZ+PI infarction was associated with a higher degree of stenosis and higher plaque-wall contrast ratio and enhancement ratio, compared with BZ only infarction, suggesting that embolic pathogenesis may also account for BZ+PI infarction in addition to hemodynamic compromise.

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