Abstract #1670

White Matter Alterations in Patients with End-Stage Renal Disease: A Diffusion Tensor Imaging Study

Yiwei Che¹, Yanwei Miao¹, Yuhan Jiang¹, Peipei Chang¹, Bingbing Gao¹, Qingwei Song¹, Ailian Liu¹, Jiazheng Wang², and Yanling Wu²

¹Department of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

End-stage renal disease (ESRD) has become risk factor for vascular disease, stroke and cognitive dysfunction, and the white matter lesions may be associated with these adverse outcomes. Silent white matter alterations may occur in the earlier stages, whereas conventional MR imaging may not be found, This study aim to detect subtle white matter alterations in patients with ESRD through diffusion tensor imaging (DTI). DTI can reflect early occult white matter damage in ESRD patients.

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