Abstract #1679

Mesoscopic imaging of perivascular spaces at 7T

Farshid Sepehrband¹, Samantha Ma², Jeiran Choupan², Sook-Lei Liew², and Arthur W Toga²

¹Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, USC, Los Angeles, CA, United States, ²USC, Los Angeles, CA, United States

Imaging of the perivascular spaces (PVS) is of growing interest, especially due to its involvement in brain clearance and blood-brain barrier exchange [1]–[3]. PVS mapping is often limited to macroscopic PVS (>1mm), which limits the study of subtle morphological PVS alteration that is expected to occur in submillimeter resolution. Here we show the advantage of ultra-high field imaging for detailed quantification of PVS in vivoand noninvasively.

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