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Abstract #1702

SWI changes in the dentate nucleus in high and low-grade brain stem neoplasms

Kamlesh Jobanputra1, Bhaswati Roy2, Karuna Raj1, Amit Agarwal1, and Frank Yu1
1Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, 2Anesthesiology, University of California at Los Angeles, Los Angeles, CA, United States

An investigation that stemmed from observation that there were dentate volume changes on SWI in low grade tumor of the brainstem showed significant decrease in signal intensity in the ipsilateral dentate nucleus in high grade neoplasms and decrease in ipsilateral dentate volumes in low grade neoplasms. We think that dentate iron deposition and its imaging is yet an unexplored field, especially in brain tumor imaging. Further evaluation with QSM and STI with histopathological correlation may also help explore pathways of iron homeostasis.

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