Meeting Banner
Abstract #1739

Do advanced fMRI and tractography preoperative evaluations correspond to intraoperative findings? A pilot evaluation in brain tumour patients.

Marco Borri1, Jose Pedro Lavrador2, Irene Brumer1,3, Enrico De Vita4, Jonathan Ashmore1,5, Francesco Vergani2, Ranjeev Bhangoo2, Keyoumars Ashkan2, and Jozef Jarosz1
1Neuroradiology, King's College Hospital, London, United Kingdom, 2Neurosurgery, King's College Hospital, London, United Kingdom, 3Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 4Department of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, London, United Kingdom, 5Department of Medical Physics and Bioengineering, NHS Highland, Inverness, United Kingdom

In this work we have evaluated the feasibility of incorporating advanced fMRI and tractography evaluations into the real-life presurgical management of patients undergoing brain lesion resections. In this pilot cohort of patients, all major preoperative imaging findings were validated by intraoperative measurements. With the inclusion of fMRI end regions, probabilistic tractography allowed a better reconstruction of the corticospinal tract and its branches in regions adjacent or within the tumour with altered or damaged fibre architecture. Robust fMRI-based language lateralization was able to describe likely dominance, in agreement with intraoperative findings and initial postoperative deficit.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here