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Abstract #1827

MR Multitasking-based Dynamic Imaging for Cerebrovascular Evaluation (MT-DICE): Development and Feasibility Study

Zhehao Hu1,2, Anthony G. Christodoulou1, Nan Wang1,2, Yibin Xie1, Bin Sun3, Xiaoming Bi4, Fei Han4, Shlee S. Song5, Marcel M. Maya6, Debiao Li1,2,7, and Zhaoyang Fan1,2,7
1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2Bioengineering Department, University of California, Los Angeles, Los Angeles, CA, United States, 3Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China, 4Siemens Healthineers, Los Angeles, CA, United States, 5Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 6Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 7Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States

Perfusion MR imaging (i.e. DCE, DSC) has evolved as an increasingly common modality for evaluating a variety of cerebrovascular diseases, such as stroke and brain tumors, and susceptibility weighted imaging (SWI) is suitable for detection of intracranial hemorrhage. In this work, we developed an MR MultiTasking based Dynamic Imaging for Cerebrovascular Evaluation (MT-DICE) technique that can provide DCE, DSC and SWI information simultaneously with one 8-minute scan and a single contrast agent injection. Feasibility of MT-DICE was demonstrated in healthy volunteers and patients with hemorrhagic stroke or brain cancer.

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