Abstract #2017

Brain activation patterns associated with sexual orientation and its correlation with free testosterone in female-to-male transsexuals

Gwang-Won Kim^1,2, Kwangsung Park^1,3, and Gwang-Woo Jeong⁴

¹Advanced Institute of Aging Science, Chonnam National University, Gwangju, Korea, Republic of, ²Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, ³Department of Urology, Chonnam National University Hospital, Gwangju, Korea, Republic of, ⁴Department of Radiology, Chonnam National University Medical School, Gwangju, Korea, Republic of

Recent functional magnetic resonance imaging studies revealed that the sexual orientation of male-to-female transsexuals have a specific tendency of female-like brain function during sexual arousal; however, the relationships between brain morphology and brain activation patterns reflecting sexual orientation in postoperative female-to-male (FTM) transsexuals are currently unknown. The purpose of this study was to evaluate the brain activation pattern associated with sexual orientation and its correlation with the level of the free testosterone in postoperative FTM transsexuals. This study was also performed to discriminate the gray and white matter volume differences between FTM transsexuals and female controls.

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