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Abstract #2058

Fast single-breathhold 2D multi-slice myocardial T1 mapping (FAST1) at 3T for time-efficient full left ventricular coverage

Li Huang1, Radhouene Neji1,2, Muhummad Sohaib Nazir1, Amedeo Chiribiri1, Reza Razavi1, and S├ębastien Roujol1
1School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Modified Look-Locker inversion recovery (MOLLI) as a commonly used myocardial T1 mapping approach shows high precision and reproducibility. Its limited capability in multi-slice acquisition per breathhold prolongs examination time in cases of desired full left ventricular coverage. The previously proposed fast single-breathhold 2D multi-slice myocardial T1 mapping (FAST1) technique can achieve time-efficient full left ventricular coverage at 1.5T. In this work, this capability of FAST1 at 3T is optimized and characterized. Compared to MOLLI, FAST1 can yield 4-fold increase of spatial coverage, limited penalty of T1 spatial variability, no significant difference of T1 repeatability and linearly correlated T1 values.

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