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Abstract #2060

3D left atrial LGE MRI at 1.5 Tesla: calibration of fibrosis cut point and initial evaluation in patients with and without atrial fibrillation

Suvai Gunasekaran1, Mohammed S.M. Elbaz1, Daniel Lee1, Michael Markl1, Rod Passman1, and Daniel Kim1
1Northwestern University, Chicago, IL, United States

Given the thin nature of the left atrial (LA) wall and the need to perform respiratory gating, the clinical translation of LA late gadolinium-enhanced (LGE) MRI has proven challenging, particularly at 1.5 Tesla. To address this, a recent study described development of a self-navigated, free-breathing 3D LA LGE pulse sequence using stack-of-stars k-space sampling and XD-GRASP reconstruction. Here, we aim to derive the cut point for LA fibrosis for this 3D LA LGE technique, by using image intensity ratio (LA wall/blood signal) of healthy volunteers, and evaluate LA fibrosis in patients with and without atrial fibrillation.

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