Abstract #2073

Macromolecular Proton Fraction Mapping Enables Endogenous Contrast Between Normal and Infarcted Myocardium.

Anna V Naumova¹, Lauren E Neidig^2,3,4, Hiroshi Tsuchida^2,3, Kenta Nakamura⁵, Charles E Murry^2,3, and Vasily L Yarnykh¹

¹Radiology, University of Washington, Seattle, WA, United States, ²Pathology, University of Washington, Seattle, WA, United States, ³Institute for Stem Cells and Regenerative Medicine, University of Washington, Seattle, WA, United States, ⁴Comparative Medicine, University of Washington, Seattle, WA, United States, ⁵Cardiology, University of Washington, Seattle, WA, United States

This pilot study shows the feasibility of fast MPF mapping in cardiac applications in the clinical magnetic field using a large-animal model. The results demonstrate that MPF maps present the effective source of the quantitative soft tissue endogenous contrast in sub-acute myocardial infarction and can be obtained with high spatial and temporal resolution.

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