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Abstract #2073

Macromolecular Proton Fraction Mapping Enables Endogenous Contrast Between Normal and Infarcted Myocardium.

Anna V Naumova1, Lauren E Neidig2,3,4, Hiroshi Tsuchida2,3, Kenta Nakamura5, Charles E Murry2,3, and Vasily L Yarnykh1
1Radiology, University of Washington, Seattle, WA, United States, 2Pathology, University of Washington, Seattle, WA, United States, 3Institute for Stem Cells and Regenerative Medicine, University of Washington, Seattle, WA, United States, 4Comparative Medicine, University of Washington, Seattle, WA, United States, 5Cardiology, University of Washington, Seattle, WA, United States

This pilot study shows the feasibility of fast MPF mapping in cardiac applications in the clinical magnetic field using a large-animal model. The results demonstrate that MPF maps present the effective source of the quantitative soft tissue endogenous contrast in sub-acute myocardial infarction and can be obtained with high spatial and temporal resolution.

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