Abstract #2124

Comparison of plaque characteristics between patients with small and large subcortical infarction using high resolution MR vessel wall imaging

Na Zhang¹, Tingting Zhu², Lijie Ren³, Lei Zhang¹, Zhangyan Fan³, Liwen Wan¹, Hairong Zheng¹, and Xin Liu¹

¹Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, ²Department of Radiology, Tongji Hospital, Wuhan, China, ³Department of Neurology, Shenzhen Second People's Hospital, Shenzhen, China

It is generally believed small subcortical infarction (SSI) (also termed lacunar stroke) is caused by intrinsic diseases of penetrating arteries. Recent studies have shown the incidence of atherosclerosis in large arteries which is an important pathogenesis of large subcortical infarction (LSI) is also high in patients with SSI. This indicates the underlying mechanisms of SSI in patients with large artery atherosclerosis may be the same with LSI and inferred from plaque characteristics. However, the plaque characteristics ultimately leading to SSI or LSI remain unclear. This study is to explore the differences of plaque characteristics between patients with SSI and LSI.

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