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Abstract #2142

3D whole heart CMRA using an image-navigator framework – a clinical comparison study with CCTA and diaphragmatic navigators

Reza Hajhosseiny1, Aurélien Bustin1, Imran Rashid1, Gastao Cruz1, Radhouene Neji1,2, Karl Kunze1,2, Tevfik F. Ismail1, Ronak Rajani1, Pier Giorgio Masci1, Claudia Prieto1, and René M. Botnar1
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Conventional diaphragmatic navigator coronary magnetic resonance angiography (d1D-NAV-CMRA) is limited by long and unpredictable acquisition-times and motion related image quality degradation. To overcome these challenges, we have previously proposed an image-navigated non-rigid motion-compensated, undersampled reconstruction CMRA framework (iNAV-CMRA) with <10min acquisition times. Here we investigated the clinical feasibility of 1.2mm3 iNAV-CMRA, comparing its performance, in patients with suspected coronary artery disease, against 1.2mm3 d1D-NAV-CMRA and coronary computed tomography angiography (CCTA). Compared to the d1D-NAV-CMRA, the iNAV-CMRA had a shorter acquisition-time(7:24±0:33min vs. 21:02±7:27min, p<0.0001), with improved coronary vessel-length, vessel-sharpness and image-quality-score, and visually comparable to CCTA.

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