Conventional diaphragmatic navigator coronary magnetic resonance angiography (d1D-NAV-CMRA) is limited by long and unpredictable acquisition-times and motion related image quality degradation. To overcome these challenges, we have previously proposed an image-navigated non-rigid motion-compensated, undersampled reconstruction CMRA framework (iNAV-CMRA) with <10min acquisition times. Here we investigated the clinical feasibility of 1.2mm3 iNAV-CMRA, comparing its performance, in patients with suspected coronary artery disease, against 1.2mm3 d1D-NAV-CMRA and coronary computed tomography angiography (CCTA). Compared to the d1D-NAV-CMRA, the iNAV-CMRA had a shorter acquisition-time(7:24±0:33min vs. 21:02±7:27min, p<0.0001), with improved coronary vessel-length, vessel-sharpness and image-quality-score, and visually comparable to CCTA.
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