Currently, CTA is the only noninvasive method with considerable evidence level for the detection and monitoring of thoracic aortic disease. However, CTA exposes patients to radiation and contrast media. The compressed-sensing whole-heart MRA technique that we evaluated addresses the limitations that prevent conventional MRA techniques to compete with CTA. Our approach eliminates the need for breath-holds or respiratory-navigation, provides a 3D volume of the chest without contrast administration, and allows for accurate anatomical evaluation of the thoracic aorta compared to CTA. Such MRA technique is a potential radiation- and contrast-free alternative for diagnosing and monitoring patients with thoracic aortic disease.