Quiescent-interval slice-selective (QISS) MRA has become established as a simple “push button” nonenhanced alternative to CTA and contrast-enhanced MRA. However, a fundamental drawback of QISS as currently implemented is that it uses a 2D acquisition strategy. The inability to acquire very thin slices along with the non-rectangular slice profile predisposes QISS to artifacts from partial volume averaging and blurring of multiplanar reconstructions. We therefore implemented and optimized a novel thin-slab stack-of-stars QISS (tsSOS-QISS) technique to provide near-isotropic high spatial resolution that rivals CTA, while maintaining the excellent arterial conspicuity, motion insensitivity and breath-hold capability of 2D QISS.
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