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Abstract #2161

An In-Vivo Assessment of Velocity Sensitivity for TOF MRA and SNAP MRA

Anders Gould1, Zhensen Chen1, Zechen Zhou2, Niranjan Balu1, Thomas Hatsukami3, and Chun Yuan1
1Vascular Imaging Lab and Bio-Molecular Imaging Center, Radiology, University of Washington, Seattle, WA, United States, 2Philips Research North America, Cambridge, MA, United States, 3Surgery, University of Washington, Seattle, WA, United States

TOF and SNAP are both useful angiographic imaging sequences. In this study, we compared signal patterns of intracranial arteries depicted by the two techniques and explored their relationship with blood flow velocity. Twenty-four subjects with carotid atherosclerosis were imaged. The number of distal intracranial branches were scored based on the MRA images. SNAP showed more variation across subjects than TOF. TOF MRA score seems more strongly correlated with carotid velocity. This suggests TOF MRA may be more robust, while SNAP MRA may be more sensitive to flow change, although the underlying mechanism needs further clarification in the future.

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