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Abstract #2207

Towards Realistic Cardiac MR Image Simulation; Inclusion of the Endocardial Trabeculae in the XCAT Heart Anatomy

Sina Amirrajab1, William Paul Segars2, Cristian Lorenz3, Juergen Weese3, and Marcel Breeuwer1,4
1Biomedical Engineering Department, Eindhoven University of Technology, Eindhoven, Netherlands, 2Carl E. Ravin Advanced Imaging Laboratories, Duke University, Durham, NC, United States, 3Philips Research Laboratories, Hamburg, Germany, 4MR R&D - Clinical Science, Philips Healthcare, Best, Netherlands

The importance of realistic cardiac MR simulation has been realized over the past decade. For this application, XCAT phantom provides realistic highly detailed whole body anatomical models including the heart and respiratory motion. Although the current XCAT heart model is complete in terms of substructures, the trabeculae structure of the endocardium, which is geometrically complex, is lacking. Based on a high-resolution ex-vivo cardiac image data, we modeled and incorporated the irregularity of the trabeculae into the existing XCAT model. We demonstrated that greater realism in cardiac MRI simulation can be achieved by including the trabeculae anatomy into the heart.

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