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Abstract #2272

In-vitro and in-vivo validation of a pediatric whole heart 4D flow acquisition in 4 minutes with compressed sensing

Takashi Fujiwara1, Lorna Browne1, Ladonna Malone1, Quin Lu2, Brian Fonseca3, Michael DiMaria3, and Alex J Barker1,4
1Department of Radiology, Section of Pediatric Radiology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 2Philips Healthcare NA, San Francisco, CA, United States, 3Department of Pediatrics, Section of Pediatric Cardiology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, 4Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

We investigate the feasibility of the accelerating 4D flow with compressed sensing and online reconstruction in pediatric patients. In-vitro models and imaging in pediatric patients was performed and hemodynamic quantification was compared to conventional approaches. The results demonstrated flow metrics and clinically relevant indices measured by 6-fold accelerated CS were in good agreement with those measured by conventional acceleration techniques, with scan time savings of 30.2%. This suggests the feasibility of using CS 4D flow for pediatric patients in the clinical setting.

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