The purpose of this study was to investigate the effect of choice of radiologist on radiomics in breast MRI. Two cohorts of 100 patients each had breast lesions segmented by 4 independent radiologists, and these segmented images used to produce 101 radiomic features. over 90% of all features were found to have good or excellent agreement across readers, and a similar number of highly significant U-test were found for all readers. Differences between reader interpretation exist, however, they would not appear to effect the ability to distinguish between benign or malignant lesions.
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