Radiomic analysis has exponentially increased the amount of quantitative data extractable from a single medical image. However, the effect of various image acquisition conditions on the reproducibility or robustness of these features is understudied. Specifically, when generating a predictive model to be used in a multi-institutional setting, it must be robust to voxel size changes. This study aims to develop a task-specific robustness preselection step for incorporation into radiomics pipeline to improve the generalizability of a model applied to a testing set of dissimilar resolution.
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