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Abstract #2331

Diffusion-weighted imaging using multiplexed sensitivity encoding (MUSE) in breast cancer: comparison with single-shot echo-planar imaging

Gabrielle C Baxter1, Andrew J Patterson2, Ramona Woitek1, Amy J Frary1, Gavin C Houston3, Martin J Graves2, and Fiona J Gilbert1
1Department of Radiology, University of Cambridge, Cambridge, United Kingdom, 2Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom, 3GE Healthcare, Buckinghamshire, United Kingdom

Diffusion-weighted images acquired using single-shot echo-planar imaging (ss-EPI) often have a low resolution and are limited by blurring and distortion. This study investigated the use of MUSE (multiplexed sensitivity encoding), a multi-shot segmented-EPI technique, in the detection and characterisation of breast cancer. MUSE showed an improvement in image quality and an increased separation of malignant from benign lesions using the normalised apparent diffusion coefficient (ADC).

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