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Abstract #2337

A Reader Study Comparing the Quality of High-Resolution Diffusion Weighted Imaging Methods for Breast MRI

Jessica A McKay1,2, An L Church3, Nathan Rubin4, Tim H Emory3, Noelle F Hoven3, Jessica E Kuehn-Hajder3, Michael T Nelson3, and Patrick J Bolan2,3
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 4Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States

Axially reformatted (AR) SMS can provide full-coverage breast DWI with high quality and 1.25 mm isotropic nominal resolution. In this work we assess the image quality of AR-SMS in a clinical setting and compare it with a standard clinical sequence and RS-EPI. Three radiologists scored DWI and ADC maps from 30 patients with enhancing lesions. All three readers scored AR-SMS with the highest quality and ranked it as superior most frequently. Accounting for reader and subject effects, a linear mixed model found that AR-SMS outperformed RS-EPI, which both outperformed the Standard with statistical significance in both quality score and rank.

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