Abstract #2337

A Reader Study Comparing the Quality of High-Resolution Diffusion Weighted Imaging Methods for Breast MRI

Jessica A McKay^1,2, An L Church³, Nathan Rubin⁴, Tim H Emory³, Noelle F Hoven³, Jessica E Kuehn-Hajder³, Michael T Nelson³, and Patrick J Bolan^2,3

¹Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States, ²Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, ³Department of Radiology, University of Minnesota, Minneapolis, MN, United States, ⁴Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States

Axially reformatted (AR) SMS can provide full-coverage breast DWI with high quality and 1.25 mm isotropic nominal resolution. In this work we assess the image quality of AR-SMS in a clinical setting and compare it with a standard clinical sequence and RS-EPI. Three radiologists scored DWI and ADC maps from 30 patients with enhancing lesions. All three readers scored AR-SMS with the highest quality and ranked it as superior most frequently. Accounting for reader and subject effects, a linear mixed model found that AR-SMS outperformed RS-EPI, which both outperformed the Standard with statistical significance in both quality score and rank.

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