Abstract #2355

Detecting regional differences of lung motion by optical flow analysis combined with rapid cine MRI using compressed sensing

Koji Sagiyama¹, Masateru Kawakubo², Ryohei Funatsu³, Takeshi Kamitani¹, Yuzo Yamasaki¹, Tomoyuki Hida¹, Yuko Matsuura¹, Yuriko Murayama¹, and Hidetake Yabuuchi⁴

¹Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ²Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan, ³Department of Medical Technology, Division of Radiology, Kyushu University, Fukuoka, Japan, ⁴Departmant of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

The application of cine MRI to lung disease has been technically challenging. In this study, we exploited optical flow analysis combined with rapid acquisition of cine MRI using compressed sensing to detect differences in regional lung motion. The high spatial and temporal resolution and higher signal-to-noise ratio of cine MRI enabled optical flow analysis to visualize regional differences between five lung segments. It also differentiated between chest and diaphragm breathing patterns in volunteers. In the future, this non-invasive method could be applied to assess and follow lung diseases, such as interstitial pneumonia or chronic obstructive pulmonary disease.

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