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Abstract #2422

Comparing multi-shot DWI with multiplexed sensitivity encoding (MUSE) with reduced field of view DWI in prostate MRI by visual grading analysis

Anugayathri Jawahar1, Ali B Syed 1, Peter Wei 1, Lloyd Estkowski2, Arnaud Guidon3, Perla Subbaiah4, Bruce Lewis Daniel1, and Andreas M Loening 1
1Body MRI, Stanford University, PALO ALTO, CA, United States, 2Global MR Applications & Workflow, GE Healthcare, Waukesha, WI, United States, 3MR Body Applications & Workflow, GE Healthcare, Boston, MA, United States, 4Mathematics, Oakland University, Rochester, MI, United States

Diffusion-weighted imaging (DWI) using echo-planar technique is highly sensitive to susceptibility artifacts, in prostate MRI this is mainly due to rectal gas. In the hopes of identifying a sequence with better robustness to rectal gas, we compared multi-shot DWI using MUSE (with 3 shots) with a rFOV-DWI acquisition. In this IRB approved prospective study, 3 readers performed visual grading of MUSE and rFOV-DWI on 50 consecutive prostate MRI studies. MUSE-DWI and ADC maps showed statistically significant improvements in image quality for anatomic contour, lesion conspicuity, and overall image quality, as well as significantly reduced susceptibility artifacts related to rectal gas.

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